Charles Explorer logo
🇬🇧

Respiratory Epithelial Adenomatoid Hamartoma

Publication at Faculty of Medicine in Hradec Králové |
2019

Abstract

Respiratory epithelial adenomatoid hamartoma (REAH) belongs to the group of benign sinonasal lesions, manifesting as an isolated lesion or in coincidence with chronic rhinosinusitis with polyps. The authors present clinical data of our REAH patients and provide an overview of the literature on the subject.

During the period 2013-2018, six REAH patients aged 48-76 (median 61.5 years) were diagnosed at the Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Hradec Kralové. Before the diagnosis of REAH, the smell disorder was detected in five cases, nasal obstruction and secretion in five patients as well.

In isolated form, REAH was found once at the posterior edge of the septum, twice in the olfactory cleft. In association with chronic rhinosinusitis with polyps, REAH was detected twice in olfactory cleft and once in ethmoids.

Five patients have been operated by endonasal endoscopic surgery, four patients under general anesthesia and one patient under local anesthesia. Five patients are followed-up without recurrence (range 5 months - 5 years, median 48 months).

One patient refused surgery and is not followed-up. Respiratory epithelial adenomatoid hamartoma is a benign sinonasal lesion.

Histological examination is essential for the differential diagnosis of lesions needing other treatment strategies. After complete surgical removal, recurrence is rare.