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Acute stress response - can we feel it in our bones?

Publication at Faculty of Medicine in Hradec Králové |
2019

Abstract

An acute stress reaction is a phylogenetically conserved response of the organism to impending or ongoing tissue damage. The reaction involves activation of the sympathetic nervous system and the neuroendocrine axis of the hypothalamus - pituitary gland - adrenal glands.

Bone tissue cells, osteoblasts, produce hormone osteocalcin, which is responsible for precipitation of the entire reaction. It increases skeletal muscle endurance, decreases insulin resistance and sharpens short term memory.

In fact, we are not dependent on the level of catecholamines in the acute phase, but their clinical indications are indisputable.