Control of electrochemical signal from silver nanoparticles at different modification steps for electrochemical immunosensor development
2018
Abstract
Development of electrochemical immunosensors towards antibody detection consists of several steps. Specific attention was paid to exclude the non-specific electrochemical signal from silver nanoparticles at different modification steps.
A tick-borne encephalitis virus antigen was attached to glutaraldehyde on a glassy carbon electrode modified with gold nanoparticles and cysteamine. Cyclic voltammetric studies demonstrate the electrochemical situation on the electrode surface by electron transfer of FeII/III as a probe.
Detection of the SNPs was performed by anodic stripping voltammetry of Ag+ at the glassy carbon electrode.