Publikace na Přírodovědecká fakulta |
2019
Abstrakt
This contribution is focused on the development of electroanalytical methods for the monitoring of anthraquinone-based anticancer drugs in physiological solution by combination of liquid-flow system and dialysis catheter, possibly inserted into blood circulation of patients. For this purpose, amperometric detection with dual glassy carbon electrode was developed and derivate of these drugs, anthraquinone-2-sulphonate, was used as a model compound.
Two different flow rates of carrier solution (physiological solution) were tested (specifically, 1 and 5 μL min-1) and the dependence of peak currents of anthraquinone-2-sulphonate on its concentration was verified.