Publication at Faculty of Medicine in Pilsen |
2019
Abstract
Cardiac magnetic resonance (CMR) imaging has an important role in detection and differential diagnosis of the myocardial amyloidosis versus hypertrophic cardiomyopathy, but especially in differential diagnosis of both types of amyloid deposits in the heart muscle - transthyretin amyloidosis (ATTR) and light chain amyloidosis (AL). Because of the most specific test to detect ATTR is scintigraphy, the transmural gradient and gradient apex to base of deposits evaluations are challenging in CMR, the imaging of the involvement in right ventricle and in atria is other important roles of CMR.
The imaging techniques of CMR suitable in cardiac amyloidosis assessment are late gadolinium enhancement (LGE) and T1 mapping.