Publication at First Faculty of Medicine |
2020
Abstract
The time factor in curative radiotherapy of squamous head and neck cancer accounts approximately for 5-10% of overall effect. Radiotherapy series duration is significantly associated with local control and every day prolonging the treatment schedule means loss of 1- 5% of local control.
Methods compensating radiotherapy prolongation have evolved and they are part oflocal treatment standards. Altered radiotherapy regimens could improve results of treatment due to shortening treatment time or application of higher radiotherapy dose.
Time factor is more important in radical than postoperative treatment. Time from diagnosis to treatment beginning is another factor contributing to disease control.