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Effect of intratracheal administration of iopamidol on the ultrastructure of the epithelium of terminal bronchioles in rabbits (Oryctolagus cuniculus var. edulis)

Publication at Second Faculty of Medicine |
1998

Abstract

The ultrastructure of the epithelium of terminal bronchioles in rabbits was studied 40 minutes after intratracheal administration of iodinated water-soluble non-ionic contrast agent iopamidol. The signs of pathological alteration of the epithelial cells may be a result of the transitional hypoxia during administration.

The secretory Clara cells were not stimulated to release their secretion, nor the signs of epithelial cells' proliferation were noticed.