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Development of the intestinal microbiome - importance for prevention and therapy

Publikace na 3. lékařská fakulta, 1. lékařská fakulta |
2020

Tento text není v aktuálním jazyce dostupný. Zobrazuje se verze "en".Abstrakt

Presented is a review of knowledge about the development of the microbiome from birth with regard to its genetic predisposition to 2 basic factors - the way of birth and nutrition of the newborn. The close relationship of microbial development to the intestinal immune system is shown.

Attention is drawn to the importance of eumicrobiosis and its preventive function in the course of metabolic processes and the prevalence of non-contagiouse diseases. A particularly serious risk of dysmicrobiosis, which is currently considered to be one of the major elements in the etiopathogenesis of many so-called civilization linked diseases, is underlined.

The importance of modulation is therefore justified, mainly by probiotics according to the classical works of Mechnikov's lactic acid milk products containing lactic - acid milk bacteria. Recently, it is also the application of "faecal microbial therapy", so far mainly in non-specific intestinal inflammations and with the prospect of its application in several metabolic, cardiovascular, neurodegenerative, autoimmune diseases, even in some mental disoders.