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COVID-19, chronic inflammatory respiratory diseases and eosinophils-Observations from reported clinical case series

Publication at First Faculty of Medicine |
2020

Abstract

Based on the current evidence and clinical observations, it could be suggested that allergic airway disease associated with eosinophilic infiltration and down-regulation of ACE2 does not represent a risk factor for COVID19 infection. Further investigations are highly needed to confirm mechanisms underlying the low prevalence of allergies and chronic inflammatory/respiratory diseases in COVID-19 patients and to clarify the clinical meaning and therapeutic consequences of eosinopenia in these patients.