Publication at Second Faculty of Medicine |
2021
Abstract
Lipoblastomas are rare, benign adipose tissue tumors that occur primarily in infants and children below 3 years of age. Although lipoblastomas are usually localized and well-circumscribed tumors, part of them can have diffuse infiltrative growth patterns known as lipoblastomatosis.
Lipoblastomatosis has a higher risk of recurrence than ordinary lipoblastoma. We describe four different PLAG1 gene fusion partners in five patients with lipoblastoma and in one lipoma.