Cluster analysis of molecular components in 100 patients suffering from atopic dermatitis according to the ISAC Multiplex testing

Abstrakt

The aim of this study is to evaluate the results in Multiplex ISAC test in atopic dermatitis patients according to the cluster analysis. Fundamental position have the components Phl p 1 (Timothy), Bet v 1 (Birch), Alt a 1 (Alternaria) followed by molecular components of NPC2 family, cystein proteasa, tropomyosin, uteroglobin, lipocalin and PR-10 protein.

Our results correspond to the association of molecular components into protein families according to their biochemical structure.

Klíčová slova

• Atopic dermatitis
• molecular components
• multiplex ISAC testing
• protein families
• biochemical structure
• cluster analysis
• silhouette