Breast cancer in metastatic stage is considered as incurable disease. About 20% of all patients have distant metastases.
The offer of new cytotoxic and biological agents caused prolongation of the overall survival in patients with metastatic disease. Eribulin is considered as the new effective cytotoxic agent for pre-treated patients with locally recurrent and metastatic breast cancer.
Vinorelbin is effective well tolerated treatment, which is important in sequence palliative treatment of metastatic breast cancer.