Abstract
The focal inflammatory intracranial diseases comprise epidural abscess, subdural empyema, septic intracranial trombophlebitis and the brain abscess (BA). BA is a relatively rare, life-threatening disease with potentially serious lifelong sequelae.
The BA incidency is given in the range of 0.3-1.8/100 000 of persons per year; up to 25% cases occur in the childhood. Predisposing factors of the BA development in children might be acute infections in the ENT area, respiratory tract infections, meningitis, infectious endocarditis associated with congenital heart malformations, arterio-venous malformations of the lung circulation, penetrating head injuries and brain neurosurgery.
The immunocompromised patients represent a special group. The etiology of BA is mostly bacterial (Gram positive cocci Streptococcus and Staphylococcus, but also anaerobic and Gram negative bacteria).
The theoretical overview about this disease illustrated by the case reports of two girls with the BA as a complication of paranasal sinuses inflammation (P1) and acute pharyngitis (P2) is presented in our work.