Abstract
Hemolytic-uremic syndrome (HUS) is thrombotic microangiopathy characterised by the presence of acute kidney injury, nonimmune hemolytic anemia and thrombocytopenia. It is one of the most common cause of pediatric acute kidney injury.
Our current understanding of the pathogenesis of HUS along with modern diagnostic and therapeutic methods significantly improved outcomes of affected patients. This review summarizes the current state of knowledge of the topic.