Immunotherapy with anti PD-1 antibodies is one of the fundamental treatment for melanoma and radiotherapy has been used for decades, especially in palliative care. Recent studies suggest that immunotherapy and radiotherapy can act synergistically and in some cases may have an abscopal effect.
In our patient, we observed, when we combined pembrolizumab with radiotherapy for nodal metastases, a significant improvement in the overal condition, including stabilization of organ metastases.