Can serological methods be helpful in the diagnosis of COVID-19 in cases of repeated false negative results of PCR tests?
2020
Abstract
We present the case report of a patient with classical symptoms of respiratory disease, who has had repeat negative RT-PCR results of the SARS-CoV-2 virus RNA, but a rapid immunochromatographic test detected the presence of IgM class antibodies, later also IgG. A typical picture of viral pneumonia in COVID-19 was also found during a CT scan of the lungs.
Even currently, in the era of fully available laboratory and microbiological examinations, a well-collected medical history, clinical examination and assessment of the course of the disease remain imperative.