The increased number of mast cells in epicardial adipose tissue is associated with coronary artery disease
Abstract
Inflammation of adipose tissue can affect its metabolic activity associated with the pathogenesis of coronary artery disease (CAD). Mast cells represent an important component of the innate defense system.
In our work, we quantified mast cell counts in epicardial adipose tissue (EAT), subcutaneous adipose tissue (SAT), and atrial myocardium (AM) in patients undergoing open heart surgery with various metabolic diseases.