Publikace na Přírodovědecká fakulta |
2020
Abstrakt
Sudan I is an aromatic azo-compound that has been proven to be a carcinogen. During its metabolization by cytochrome P450 in liver a few main derivates can be identified.
This work sets out to assess the mechanism of electrochemical reduction and oxidation of Sudan I, its hydroxylation derivatives featuring metabolites in the Sudan I detoxification pathway and to introduce their selective voltammetric analysis on boron-doped diamond electrode. We show successful differentiation among these compounds, thanks to the differences in the electrochemical oxidation of their phenolic groups.