Abstract
Progressive supranuclear palsy is a tauopathy belonging to atypical Parkinsonian syndromes. The main clinical symptoms include oculomotor dysfunctions, early postural instability, symmetrical hypokinetic-rigid syndrome with axial predominance and cognitive decline.
The symptom variability and rate of progression depend on disease subtype. Dia gnostics are based on clinical symptoms; MRI remains the most useful auxiliary method.
The article is focused mainly on clinical perspectives and recent dia g nostic approaches considering the latest recommendations. Symptomatic therapy remains of great importance as causal treatment is still lacking.