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Self-disorders as a schizophrenia endophenotype - a review

Publication at Faculty of Arts |
2020

Abstract

Diagnosis of schizophrenia has been tradition-ally linked to symptoms that can be described broadly as a disruption of the basic sense of self. These symptoms encompass, for example, symptoms of passivity as in the case of delu-sion of control, thought withdrawal, or auditory hallucinations, i.e. symptoms in which patients excessively over-attribute their own activity to some external forces.

In general, these symptoms are characterized by the disturbance of the demarcation between self and others. Recent ac-counts underline the fact that, similarly to other traits or mental illnesses, symptoms of schizophrenia are present on a continuum.

Thus, they can be found in the general population. Due to their genetic underpinnings, these traits are of-ten more pronounced in unaffected relatives of schizophrenia patients.

This review analyzes self-disturbances as a potential endophenotype of schizophrenia, which is expressed on a con-tinuum