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Management of Concomitant Abdominal Aortic Aneurysm and Intra-abdominal, Retroperitoneal Malignancy

Publication at Faculty of Medicine in Pilsen |
2021

Abstract

Background/Aim: As the population ages, there are increasing findings of coincidental diseases such as abdominal aortic aneurysm (AAA) and intra-abdominal, retroperitoneal malignancy. The aim of this study was to propose an optimal treatment procedure for these patients.

Patients and Methods: Over a twenty-year-period, surgery was performed on a total of 1,098 patients with AAA and 32 (2.9%) patients with AAA and intra-abdominal, retroperitoneal malignancy: 18 renal, 6 colorectal carcinomas, 3 carcinomas of the small intestine, 3 primary liver tumours, 1 stomach carcinoma and 1 teratoma. The median age of patients was 72.5 years, there were 20 men (62 5%) and 12 women (375%).

A one-stage procedure was performed on 19 patients (59.4%), and a two-stage procedure on 13 (40.6%) patients. Results: The average time of hospitalization was 12.4 +/- 6.9 days (median.11.0 days) for one-stage procedure, for a two-stage procedure 213 +/- 93 days (median=20.0 days), p=0.0045.

Seven patients (21.9%) died within 30 days after the operation. All the deaths were in the group of one-stage procedures (p=0.0252).

The 1-, 3- and 5-year overall survival for patients following one-stage and twostage procedures was 61.0/563/515% and 89.0/79.9/53.0% respectively (p=0.1199). Conclusion: Symptomatic disease must be resolved first.

Tivo-stage procedures are the method of choice and offer better short-term results compared to onestage procedures.