Abstract
The book presents a multidisciplinary review of cancer associated trombosis (CAT). The introduction contributes with epidemiologic data about the incidence and consequences of venous thromboembolism (VET) in general population and particularly in cancer patients.
The following part explains the etiopathogenic links between thrombosis and cancer, including the overview of potential prothrombotic effects of various types of antitumor treatment. The next topic is cancer screening in patients with unprovoked VTE, its indications and extent.
The authors also describe the possibilities of CAT prevention in hospitalized patients as well as in ambulatory patients with chemotherapy, including new data about direct oral anticoagulants in the indication. Later on, the book deals with the diagnosis and treatment of CAT, informs about recent guidelines, concerning also the use of direct oral anticoagulants and oncology mediations.
Some situations complicating the treatment of CAT are mentioned, e.g. thrombocytopenia or bleeding. Specific topics are the interventional treatment of superior vena cava syndrome; the use of inferior vena cava filters in cancer patients; thromboses in unusual sites and central venous catheter thrombosis.
The authors mention also some less common manifestations, as superficial vein thrombosis or atherothrombosis in cancer patients. Moreover, some ethical dilemmas associated with the prevention and treatment of CAT in terminal stages of cancer are discussed.
Finally, the book submits a practical view on the care of patients with CAT on an outpatient basis in our healthcare system.