Letter to the Editor from Brunerová et al: "Association of Cognitive Function and Retinal Neural and Vascular Structure in Type 1 Diabetes"
Abstrakt
We read with much interest the paper written by W. Fickweiler et al in the Journal of Clinical Endocrinology & Metabolism on the association between optical coherence tomography (OCT)/OCT angiography and cognitive dysfunction in patients with type 1 diabetes mellitus (T1DM).
However, we would like to focus on 4 methodologic aspects. Firstly, mood disorders were not excluded in the participants.
Secondly, the influence of neuropathy on cognitive functions in TDM1 has already been proven. Thirdly, premorbid intellect or education were not evaluated as independent variables in the correlation of cognitive functions and OCT, although lower general intelligence may represent a risk factor for both, the onset of dementia and the rate of cognitive decline in aging through the mechanism of cerebral reserve.
Fourthly, glycemia was not measured before the complex cognitive testing.