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The Histomorphometric Analysis of Maxillary Sinus Lift Elevation Using the Synthetic Hydroxyapatite and Tricalcium Phosphate Grafting Materials

Publication at Second Faculty of Medicine |
2021

Abstract

The aim of the study was to conduct an evaluation of the success of implants inserted into the distal maxilla augmented via the lateral sinus lift method using a combination of synthetic alloplastic hydroxyapatite and beta-tricalcium phosphate materials. The solubility of PORESORB-TCP in body fluids leads (due to TCP dissolution) to their hyper-saturation with Ca2+ and P ions, which gradually reprecipitate as CaP.

OssaBase-HA has been shown to evince osteoconductive properties. The aim was to take advantage of the synergistic osteoconduction potential of the hydroxylapatite OssaBase-HA and beta-tricalcium phosphate PORESORB-TCP materials.

We selected a ratio of the two materials of 3:2 for experimentation purposes. The histological findings clearly indicated that, concerning the histological sample, the area of the original bone was 21.4 % and the area of augmented tissue occupied 78.6 %.

The proportion of bone of the patients' hard tissue was 68.3 % compared to 43.9 % of bone with the new augmented tissue. The volume of the augmentation material in the augmented tissue was determined at 45.6 %.

The amount of PORESORB-TCP was 34.1 % of the augmentation material, and the amount of OssaBase-HA was 11.6 % of the augmentation material. Our study thus confirmed the osteoconductive properties of the hydroxylapatite OssaBase-HA and beta-tricalcium phosphate PORESORB-TCP materials and demonstrated the osteoconduction of a 3:2 mixture of the two materials, thus proving the synergy of their respective properties.