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Locally advanced cervical cancer - change of the original indication of palliative radiotherapy to radical radiotherapy and achievement of complete remission

Publication at Faculty of Medicine in Pilsen |
2021

Abstract

Cervical cancer is the tenth and fourth most common cancer in women in the Czech Republic and worldwide, respectively. The standard treatment approach for locally advanced cervical cancers is radical radiotherapy (RT), optimally potentiated by concomitant chemotherapy.

This approach leads, with the use of modern radiotherapeutic procedures and with the correct indication, to a high probability of achieving complete remission and a low probability of severe late post-radiation morbidity. In the presented case report, we deal with the case of a patient with locally advanced cervical cancer who first refused to undergo standard treatment, but after escalating bleeding symptoms agreed to undergo palliative RT, which was at the last minute prudently changed to radical RT, combining external beam RT and MR based 3D uterovaginal brachytherapy, allowing complete remission of the disease.