Abstract
SARS-CoV-2 virus which is pandemic is entering host cells via interaction between viral spike glycoprotein S with membrane bound ACE2 enzyme. All cells expressing ACE2 are infectable by SARS-CoV-2 virus.
The natural course of COVID-19 diseases which is caused by SARS-CoV-2 infection is very individual. It is caused especially by individual immune reactivities.
Those infected people who are unable to control and eliminate SARS-CoV-2 infection effectively can progress into severe harm inflammatory response affecting especially respiratory tract. However, SARS-CoV-2 virus could be recognized as neurotropic.
Cellular structure of CNS are expressing ACE2 viral receptor. There are several putative ways for SARS-CoV-2 to enter CNS.
Patients with multiple sclerosis are not at increased risk of SARS-CoV-2 infection. These patients will profit from active immunisation against SARS-CoV-2.
This immunisation will induced at least partial protection against SARS-CoV-2 with very limited risk of harm effects of immunisation.