Changes in trace elements (Mn, what he Cu, Rb, Mo and Ba) in the bone of the lower jaw of the rat after interruption of the nerve alveolaris inferior
Abstract
Objective: The purpose of the study was to test the effect of transection the inferior alveolar nerve on selected trace elements in the mandibular bone of the rat. Material and methods: We used 7-9 weeks old males of Wistar laboratory rats for the study.
The animals were divided in three groups: control (intact) group, experimental group (with the nerve transected on the left) and the sham group (the nerve was only exposed, not transected). The animals were sacrificed 4 weeks later and their teeth were extracted (not part of the study).
The mandibular bone was divided in 4 parts. Inductively coupled plasma mass spectrometry was used to determine 7 elements in the bone.
Results: As follows from the study, nerve transection resulted in decreased contents of cobalt, nickel and barium. Furthermore, it resulted in disappearing of rubidium content differences on the left and right side of the mandible.
The surgical approach itself causes changes in the distribution of rubidium, molybdenum and barium contents of the mandible and disappearance of the left and right side difference for barium in the ridge and for nickel at the mesial location and in the ridge. No substantial differences were observed for manganese and copper.
The described changes are probably related to a certain remodelling of the cancellous bone and its loss, as noted by others. Conclusion: The results support our hypothesis stating that sensory innervation affects trace elements in the mandibular bone.