Fibrous hamartoma of infancy: A study of eight cases with immunohistochemical and electron microscopical findings

Abstract

Eight cases of fibrous hamartomas of infancy are presented. Actin positivity and desmin negativity in collagen forming spindle-shaped cells and electron microscopical findings point to the myofibroblastic nature of this entity. ''Dark cells'' which spread regularly in all but one of our tumors were immunohistochemically determined to be a mixture of B and T cell lymphocytes.

Their selective location and possible role are discussed.

Keywords

• Hamartoma
• Spindle cell tumor
• Dark cells
• Infancy tumors