Let me introduce to you a case report of the meningeal form of Rosai-Dorfman disease (RDD). RDD (or sinus histiocytosis with massive lymphadenopathy), is a rare hematologic disease characterized by nonmalignant proliferation and accumulation of a specifi c type of leukocytes (histiocytes), that primarily aff ects lymph nodes, but it can also aff ect most organ systems in the human body, including the CNS.
This disease aff ects both males and females under the age of 20. The etiology remains unknown.
Most common symptoms include painless enlargement of the lymph nodes; overall, symptoms, such as fever, paleness, weight loss or malaise, and other specific symptoms depend on the affected organ.