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Thrombophilic conditions during pregnancy

Publication at First Faculty of Medicine |
2021

Abstract

Thromboembolic events are among the most feared complications of pregnancy and are still at the forefront of maternal morbidity and mortality in civilized countries. The increased risk of deep vein thrombosis in pregnancy is due to both physiological changes during pregnancy and associated risk factors.

Thrombophilic conditions are also often manifested for the first time in pregnancy. Thrombophilia is a congenital or acquired disorder of the hemostatic mechanism, characterized by an increased tendency for blood clotting and thrombosis.

In pregnancy, thrombophilia exceeds not only the risk of a venous thromboembolic event, but also the risk of other conditions associated with intravascular thrombogenesis.