Abstract
Fibrous dysplasia (FD) is a congenital skeletal disease characterized by the presence of bone lesions containing fibrous connective tissue. FD occurs in monoostotic or polyostotic form.
Rarely, fibrous dysplasia is part of McCune-Albright syndrome together with "café au lait" cutaneous hyperpigmentations and endocrine hyperfunction (especially pubertas praecox, thyrotoxicosis, Cushing's syndrome, etc.). Clinical symptomatology depends on the extent of the bone disease.
Most bone lesions in FD are asymptomatic, with a minority of bone lesions manifesting as pain, bone deformity, or pathological fracture. The following article provides a brief overview of current knowledge about fibrous dysplasia.