Abstract
Gynecomastia is a common finding in a male population. Regarding the literature we can estimate that approximately 3-16 % of male population has drug induced gynecomastia.
Drugs are causing gynecomastia by variety of mechanisms, some of them are yet to be found. It is not surprising that among hormonal medications there are plenty of drugs with gynecomastia as an adverse effect.
Other well-known drugs which can induce gynecomastia are spironolactone, omeprazole, some calcium channel blockers, some antiretroviral drugs, some antipsychotics, ethanol and alkylating agents. There are also lot of drugs which are speculated to cause a gynecomastia, however there is not enough evidence to support it.