Potent E. coil M-17 Growth Inhibition by Ultrasonically Complexed Acetylsalicylic Acid-ZnO-Graphene Oxide Nanoparticles
2021
Abstrakt
A single-step ultrasonic method (20 kHz) is demonstrated for the complexation of acetylsalicylic acid (ASA)-ZnO-graphene oxide (GO) nanoparticles with an average size of <70 nm in aqueous solution. ASA-ZnO-GO more efficiently inhibits the growth of probiotic Escherichia coli strain M-17 and exhibits enhanced antioxidant properties than free ASA and ASA-ZnO in neutralization of hydroxyl radicals in the electro-Fenton process.
This improved function of ASA in the ASA- ZnO-GO can be attributed to the well-defined cone-shaped morphology, the surface structure containing hydroxyl and carboxylate groups of ZnO-GO nanoparticles, which facilitated the complexation with ASA.