The highlight of the World Stroke Congress in Istanbul, 2014, was the presentation of the Dutch randomised trial - MR CLEAN - the first study demonstrating the superiority of catheter-based thrombectomy (CBT) over the best medical therapy, including intravenous thrombolysis1. Just a few months later, a series of randomised trials, performed in various countries, confirmed these initial results.
All of these trials demonstrated improved functional outcomes, but the differences in overall mortality were not significant.