Biological treatment of severe atopic dermatitis in an adolescent patient

Abstract

We are presenting a case report of a boy with severe atopic dermatitis refractory to systemic immunosupresive treatment with growth retardation, secondary hypocorticalism after repeated systemic corticotherapy. Treatment with monoclonal antibody inhibiting alpha subunit of interleukin 4 receptor (IL-4Rα) dupilumab was successfull.

Keywords

• atopic dermatitis
• systemic immunosuppresive therapy
• dupilumab
• type 2 inflammation