Abstract
Infantile hemangiomas (IH) are the most common tumors in childhood. The vast majority of them do not require any treatment because they do not cause any problems or complications and spontaneously involve over months to years, 10-15% of infantile hemangiomas can cause complications: obstruction, ulceration or severe cosmetic defects that require proper therapy.
The prevalence of IH in mature newborns and infants ranges between 4-5% and are up to 3 times more common in girls. The incidence increases with decreasing gestational age and birth weight, with neonates with a birth weight below 1000 g having IH in up to 23% .2 Overall, IH affects 10-12% of infants.
Other risk factors include recurrent pregnancy, maternal age, in vitro fertilization, preeclampsia and placental abnormalities. In the differential diagnosis in neonates, we must consider congenital hemangiomas, which include RICH (rapid involuting congenital hemangioma) and NICH (noninvoluting hemangioma), which include caposiform hemangioendothelioma, tufted angioma, pyogenic angioma, and multifocal endothelioma.