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ALEX2 multiplex examination - results of specific IgE to fish and shrimps in patients suffering from atopic dermatitis

Publication at Faculty of Medicine in Hradec Králové |
2022

Abstract

The sensitivity of ALEX2 Allergy Explorer test in patients suffering from atopic dermatitis and clinical reactions to fish/shrimps was evaluated. We compared the results of specific IgE to allergen reagents (molecular components) and clinical reactions in the open exposure test (patient's history); the sensitivity was calculated with Fisher's Exact test (Rates and Confidence Intervals 95% C.

I., value, lower, upper). Altogether 100 atopic dermatitis patients were examined.

We confirmed significant relationship between the results of specific IgE to allergen reagents (molecular components) of fish and the results open exposure test/history; the sensitivity is in the range of 33.3% (7.49%-70.07%)-44.4% (13.7%-78.80%). We did not confirm the significant relationship between the results of specific IgE to allergen reagents (molecular components) of shrimps and the results open exposure test/history; the sensitivity is in the range of 0%-40% (5.27%-85.34%).