Abstract
We have read with interest the "Matters Arising" text of Kurt Jellinger, in which he comments on some parts of our recent paper. To our statements: "a) that from the strict pathological point of view, there is practically no difference between PD and PDD; even the experienced neuropathologist is not able to differentiate, and (b) that there is no sharp pathological border between PDD and DLB, although the degree of AD pathology and the presence of CAA are probably the most significant pathological differences between these two phenotypes" adds Dr.
Jellinger exceptionally valuable personal experience gained from decades of neuropathological research in parkinsonism and atypical parkinsonism. We are aware of his seminal works from 2007 and 2010 in which he reported autopsy findings in parkinsonian patients and also the differences between findings in those demented and those not.
Indeed, we have also (very recently) carefully studied his last paper on this topic from 20224, in which he has broadly discussed the study of Hansen et al.