Current views on the pathophysiology, diagnosis and treatment of immune thrombocytopenia in children

Abstract

The review summarizes the most recent knowledge of the epidemiology, pathophysiology, current diagnostic aproach and treatment strategies in immune thrombocytopenia in children.

Keywords

• antiplatelet antibodies
• immune thrombocytopenia
• immunosupressive treatment
• molecular mimicry
• platelet desialylation
• quality of life
• splenectomy
• T-cell mediated platelet destruction
• TPO mimetics