Publication at Second Faculty of Medicine |
2023
Abstract
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides are rare disorders in childhood with a variable clinical presentation. Given ANCA vasculitides' rarity, data informing clinical practice and treatment are mainly based on adult data.
The purpose of this study was to characterise clinical characteristics of ANCA-associated glomerulonephritis (AAGN) in childhood to determine factors associated with adverse renal outcome and the requirement for kidney replacement therapy (KRT) across a global study population.