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Candida sojae: First report of a human infection

Publication at First Faculty of Medicine, Second Faculty of Medicine |
2022

Abstract

Invasive candidaemia (IC) is the 4th most frequent cause of bloodstream infection and has a high mortality rate (> 50%). Candida albicans is the most frequently detected yeast species, followed by C. glabrata, C. parapsilosis, C. tropicalis and C. krusei.

Other Candida species represent only up to 10% of blood stream isolates. We describe a case of a polymorbid man with a history of robotic radical prostatectomy for non-metastatic prostate adenocarcinoma in 2010 and radical cystectomy for multifocal urothelial carcinoma in situ in 2012.

This is the first report of human isolate of C. sojae. Candida sojae is phenotypically closely related to Candida albicans and Candida tropicalis and might, therefore, be an emerging pathogen misidentified by routine mycological methods.

Susceptibility testing did not reveal any evident resistance. Appropriate treatment by echinocandin and central venous catheter removal led to recovery of the patient.