Most cases of SARS-CoV-2 infection are asymptomatic or have only mild respiratory symptoms. Patients with risk factors, including but not limited to advanced age, obesity, cardiovascular diseases and immunosuppression, may develop a severe course of disease due to the development of a cytokine storm.
COVID-19 is associated with an increased risk of bleeding and thromboembolic complications, with the gastrointestinal tract and CNS being among the most frequent sites of bleeding. One of the causes of vessel wall rupture and subsequent bleeding in COVID-19 may be dysfunction of the damaged endothelium.
Viral infections are one of the most potent triggers of autoimmune diseases. One of the possible causes of haemorrhagic stroke is virus-induced acute vasculitis.