Abstract
Background and aim: To analyse the sensitisation profile to molecular components of mites allegens with use of ALEX2 Allergy Explorer test in Atopic dermatitis (AD) patients. Method: The complwtw dermatological and allergological examination including the examination of the sensitisation to molecular components with ALEX2 Allergy Explorer testing was performed.
For the statitical analysis, we used Fisher's Exact. Result and conclusion: The sensitisation to mites increases with AD severity.
The central role in atopic march may play the molecular component Der f 2 and Der p 23- The results of our study confirm the important role of Der p 5 and Der p 7 in supgroup of patients suffering from bronchila asthma. The specific immunotherapy should focus on the components of NPC2 family and Der p 23 in AD patients.
Our results may be helpful in plannig hyposensitisation, treatment and immunotherapy.