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Monogenic diabetes - from genetics to treatment

Publication at Second Faculty of Medicine |
2009

Abstract

Apart from the two main forms of diabetes, there is a third group, about which relatively little is known among the medical public. These people have diabetes caused by a defect in just one single gene. That is why it is called "monogenic diabetes".

In families, the disease is inherited, in each generation of ancestors we usually find an individual with diabetes. Monogenic diabetes is rarely manifested already in a newborn child or in the first year of life, more often in late childhood or early adulthood. It then lasts a lifetime, so even older people can have this form of diabetes. Monogenic diabetes is often misdiagnosed and treated as type 2 or type 1 diabetes - because these forms are more common and better known.