Publikace na 1. lékařská fakulta, Fakulta tělesné výchovy a sportu, 2. lékařská fakulta |
2022
Abstrakt
Salicylate poisoning is one of the most common drug overdose scenarios. During 1983 and 1984 in Ontario, salicylates were responsible for most of the single-drug deaths. Mild intoxication presents as lethargy, nausea, vomiting, tinnitus and dizziness; and moderate (BSC 500-700 mg/l) as tachypnea, hyperpyrexia, respiratory alkalosis, metabolic acidosis, restlessnessand diaphoresis. Severe poisoning (>750 mg/l) causes hallucinations, convulsions, coma, cerebral and pulmonary edema and acute kidney injury.