Abstract
In addition to glucose metabolism disorders, type 2 diabetes mellitus is also characterized by significant changes in fat metabolism - not only cholesterol, but also non-esterified fatty acids, among other things. These changes have a negative impact on insulin signaling pathways.
For diabetics, it is important to focus not only on reaching LDL-cholesterol target values, but also on the value of non-HDL-C, which expresses the cholesterol content in all atherogenic lipoprotein particles, and also on the concentration of apoprotein B, which very well determines the number of atherogenic particles.