Small-bowel capsule endoscopy and device-assisted enteroscopy for diagnosis and treatment of small-bowel disorders: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2022
Abstrakt
Introduction: The introduction of small-bowel capsule endoscopy (SBCE) and device-assisted endoscopy (DAE) over 20 years ago marked the beginning of a new era for investigating the small intestine. There is now more solid scientific evidence on established indications, and more data on new applications of enteroscopy are available.
The aim of this Guideline, commissioned by the European Society of Gastrointestinal Endoscopy (ESGE) as an update of the previous 2015 Guideline [1], is to provide guidance for the clinical application of enteroscopy techniques in the management of adult patients with small-bowel (SB) disorders. Methods: ESGE commissioned this clinical Guideline (ESGE Guideline Committee Chair, K.T.) and appointed a guideline leader (M.P.) who formed a coordinating team (M.P., E.R., P.C.V.).
The guideline leader established six task forces, each with its leader (C.S., E.D., M.K., D.S.S., T.M., X.D.). Key questions were prepared by the coordinating team according to the PICO (patients, interventions, controls, outcomes) format and divided among the six task forces (see Table 1 s, Key Questions, available onlineonly in Supplementary Material).
Given that this is an update of the 2015 ESGE Clinical Guideline [1], each task force performed a structured, systematic search, using keywords, for available literature (English-language articles) from December 2014 to November 30 2021 in Ovid MEDLINE, EMBASE, Google Scholar, and the Cochrane Database of Systematic Reviews; the literature search was then updated up to April 1 2022, to look for recently released papers. A dedicated manual search was also performed in the same timeframe by checking references of relevant papers.
The hierarchy of studies included in this evidence-based guideline was, in decreasing order of evidence level: published systematic reviews/meta-analyses, randomized controlled trials (RCTs), prospective and retrospective observational studies, and case series.