Hyaluronic acid (HA) is an acidic, non-sulfated glycosaminoglycan that is intensively studied as a biodegradable and biocompatible material for scaffolding, regenerative medicine, and clinical applications. As the ubiquitous component of the extracellular matrix, HA is widely distributed in the human body and can be found in the umbilical cord, synovial fluid, dental pulp, vitreum, or epithelial and connective tissues. The main functions of HA are hydration, space-filling capacity, lubrication, and forming of the framework through which cells migrate. It also contributes to fetal healing of wounds, i.e., rapid healing without a scar, and tissue elasticity.
The main aim of this Biomolecules Special Issue Hyaluronic Acid in Human Medicine was to gather the knowledge about studied potential applications of hyaluronic acid worldwide. We collected 11 articles which from 7 are original papers, 3 are reviews and 1 is a case report. The Special Issue Hyaluronic Acid in Human Medicine articles are based on preclinical and clinical research and studies. The articles include many different branches of medicine, e.g., cell banking, skin healing, vocal cord augmentation, healing of osteoarthritis, ophthalmology, lung immunity, surgery, and dentistry. Therefore, the Biomolecules Special Issue Hyaluronic Acid in Human Medicine represents unique outline of possible variety usage of hyaluronic acid within the latter-day and future medicine.