A specialized multidisciplinary team (MDT) plays a crucial role in optimizing the treatment procedure for anal squamous cell cancer (ASCC). Very early stages are treated only with surgery (<5%), more advanced stages with chemoradiotherapy (CHRT).
New regimens of radical CHRT and palliative chemotherapy (CHT) and immunotherapy have shown improved survival. Modern techniques of radiotherapy (RT) lead to a significant reduction in the toxicity of the treatment and enable ambulatory administration of the treatment.