This book represents a collection of selected papers that were presented by their authors at the "European Constitutionalism and the Virus of Distrust" conference that took place on the 27-28 April 2022 at the Law Faculty of Charles University in Prague, Czech Republic. The conference was organized by the Department of Constitutional Law as a reflection of growing tensions between the functioning of national and international institutions on one side and the perception of their modes of governance by the European society on the other side.